产品货号：
Z15597
中文名称：
CYP11A1抗体
英文名称：
Anti-CYP11A1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CYP11A1 Antibody |
| 指标别名 | Cholesterol desmolase;CYP11A;CYP11A1;CYPXIA1;Cytochrome P450 11A1;Cytochrome P450(scc);P450SCC |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F |
| 基因名称 | CYP11A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human CYP11A1(507-521aa ISFTFWPFNQEATQQ). |
| 实际分子量 | 50～60KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CYP11A1(Cytochrome p450,family 11,subfamily A,polypeptide 1),also called CYTOCHROME P450SCC,CYTOCHROME P450C11A1 or CYP11A,is a mitochondrial enzyme associated with the conversion of cholesterol to pregnenolone.CYP11A1 is a member of the cytochrome P450 superfamily of enzymes.The CYP11A1 gene is mapped on 15q24.1.Expression of the CYP11A1 gene may play a role in skin physiology and pathology and that cutaneous proopiomelanocortin activity may be autoregulated by a feedback mechanism involving glucocorticoids synthesized locally by Slominski et al.Using in vitro studies,CYP11A1 catalyzed the side-chain cleavage of 7-dehydrocholesterol to form 7-dehydropregnenolone.In addition,CYP11A1 catalyzed the metabolism of biologically inert vitamin D3,which is formed from 7-dehydrocholesterol,to form 2 hydroxylated products,20-hydroxyvitamin D3 and 20,22-dihydroxyvitamin D3.Mutations in the CYP11A1 gene cause congenital adrenal insufficiency with partial or complete 46,XY sex reversal. |
| Uniprot ID | P05108 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cytochrome P450,family 11,subfamily A,polypeptide 1 |
| 蛋白名全称 | Cholesterol side-chain cleavage enzyme,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：CYP11A1抗体，CYP11A1多抗，Anti-CYP11A1 Antibody